Total concentration of weak acids
and bases ([A
TOT
])
•
Weak electrolytes (HA)
–
Partially dissociated (H
+
, A
-
) in H
2
O
–
•
[A
TOT
] = [PP] x 0.21
(mEq/L)
–
(K
A
= 2.1 x 10
-7
Eq/L)
•
•
Most important in plasma = plasma proteins